Peficitinib 4413 Smiles: CCCCCCCCCCCCCCCC(=O)O[C@@H]1CC2=CC[C@H]3[C@@H]4C[C@@H]5O[C@]6(CC[C@@H](C)CO6)[C@@H](C)[C@@H]5[C@@]4(C)CC[C@@H]3[C@@]2(C)CC1

Smiles: CCCCCCCCCCCCCCCC(=O)O[C@@H]1CC2=CC[C@H]3[C@@H]4C[C@@H]5O[C@]6(CC[C@@H](C)CO6)[C@@H](C)[C@@H]5[C@@]4(C)CC[C@@H]3[C@@]2(C)CC1

Curr Top Med Chem

m-PEG37-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs

Cardamonin does not significantly reduce HEK293 cell viability

Peficitinib 4413 Smiles: CCCCCCCCCCCCCCCC(=O)O[C@@H]1CC2=CC[C@H]3[C@@H]4C[C@@H]5O[C@]6(CC[C@@H](C)CO6)[C@@H](C)[C@@H]5[C@@]4(C)CC[C@@H]3[C@@]2(C)CC1Peficitinib is an oral JAK inhibitor, with IC50s of 3. 9, 5. 0, 0. 7 and 4. 8 nM for JAK1, JAK2, JAK3 and Tyk2, respectively. Product information CAS Number: 944118 01 8 Molecular Weight: 326. 39 Formula: C18H22N4O2 Chemical Name: 4 {[(1R,2r,3S,5s,7s) 5 hydroxyadamantan 2 yl]amino} 7H pyrrolo[2,3 b]pyridine 5 carboximidic acid Smiles: N=C(O)C1=CNC2=NC=CC2=C1N[C@@H]1[C@H]2C[C@@H]3C[C@@](O)(C[C@H]1C3)C2 InChiKey: DREIJXJRTLTGJC KDJQDEFKSA N InChi: